If a healthy and adapted diet with regular sports practice are the sine qua non conditions for losing weight, some men and women are still tempted to take a dietary supplement to dislodge their extra pounds. In the department of fat burners and other appetite suppressants is added a new product that has recently made so much talk about it: Mysimba.
Indeed, the arrival of Mysimba has created a real controversy because of the marketing authorization of the product, despite the refusal of the ANSM (National Agency for the Safety of Medicines and Health Products). Marketed by the Californian laboratory Orexigen Therapeutics, Mysimba is a combination of two active ingredients, also very famous. Therapeutic properties, side effects… Let's take stock of this new formula to lose weight, and see where to buy mysimba online in a secure way.
Why use an appetite suppressant drug?
As the name suggests, an appetite suppressant product aims to reduce appetite in order to limit snacking, which is the main cause of weight gain. By taking an appetite suppressant, you will be less tempted by the call of the closet filled with chips or sweets.
To achieve its goals, the appetite suppressant supplement acts in two ways:
- It fills the stomach by swelling in contact with water, which brings a feeling of fullness to the body.
- It directly activates leptin (satiety hormone) and attacks ghrelin (hunger hormone) in order to create a feeling of satiety.
However, you should know that an appetite suppressant is not taken on a whim. This slimming food supplement must above all be used in combination with a healthy diet and regular sports practice to help you regain a dream figure.
Many people wonder what differences there are between a conventional fat burner and an appetite suppressant. As we had just seen, the appetite suppressant promotes the feeling of satiety to limit overeating and prevent the installation of fats and therefore avoid weight loss. On the other hand, other food supplements act well on the installation of fat: they are called fat burners, because they will increase body temperature in order to burn calories, and induce a lipolytic effect that will dislodge fat from the body.
What is Mysimba, this slimming drug?
Let us now turn to the subject that really interests us. We know that Americans are the champions of overweight and obesity (in the United States, 2 out of 5 adults are obese). So it's no wonder that the majority of treatments and drugs to beat obesity come from Uncle Sam's land. Thus, after the famous alli slimming pill (now banned in France), it is Mysimba's turn to bring its benefits as an appetite suppressant drug. What is this medicine? Is this the new miracle treatment? What are the risks with this pill?
Mysimba is a slow-release drug that helps with weight loss in combination with a controlled calorie diet and regular physical activity. It contains two main ingredients: naltrexone and bupropion, which act on the brain to inhibit the urge to snack.
In fact, when we eat, our brain induces a sense of reward and positive stimuli. So when we eat more than we need, it continues to give us that feeling of reward, which is one of the reasons why some people eat too much and struggle to manage their diet.
The first component of Mysimba, naltrexone is officially known as an opioid antagonist, while bupropion is an inhibitor of norepinephrine and dopamine. Naltrexone reduces the feeling of hunger that we sometimes feel even if we are not actually hungry. For its part, bupropion is an appetite suppressant, which means that it saves you from going hungry in order to help you eat less.
You should also know that bupropion is the main ingredient of some antidepressants. This is why it is not recommended to take Mysimba in combination with antidepressant medications.
Generally speaking, the Mysimba pill is usually prescribed to people who are severely overweight, for a BMI above 30. As a reminder, BMI (body mass index) is a parameter that depends on each individual and is established according to the weight, height and age of each person.
As a reminder, obesity is a dangerous medical pathology that can affect your state of health. It can increase the risk of diseases such as type 2 diabetes, heart problems, high blood pressure, arthritis and certain types of cancer.
Obesity and weight gain can be caused by several factors, including:
- a poor diet, consisting in particular of foods high in sugar and fat,
- stress and anxiety,
- depression,
- taking certain medications,
- genes predisposing to overweight,
- and a sedentary lifestyle.
In 2016, the WHO warned of the growing proportion of people who are overweight worldwide: 39% of women and men aged 18 and over were overweight worldwide. To answer this problem, several solutions exist: in addition to sport and adapted healthy eating, you can turn to appetite suppressant food supplements such as Mysimba.
In fact, Mysimba is a slimming product that allows you to eliminate your fat if you do not feel able to lose weight simply with sport and targeted diet. Indeed, some people do not burn calories as fast as others. And combined with poor eating habits and a lack of sports practice, this situation can cause obesity, which has a major impact on health.
The main ingredients of Mysimba
As we have just seen, each tablet of Mysimba contains two key ingredients:
- Naltrexone (90 mg), an active ingredient that allows people addicted to alcohol or drugs to get rid of this addiction. Naltrexone actually belongs to the family of medications called opioid antagonists. It has the ability to stimulate the brain to prevent opiate effects, such as relieving pain and feelings of well-being.
- Bupropion (78 mg): This is an antidepressant that is effective in helping to quit smoking, as it can reduce the urge to smoke and reduce the effects of nicotine suppression.
You're probably wondering why such drugs have come to fight weight loss. Well, it's simple: researchers have noticed that some people treated with bupropion as an antidepressant lose weight. They then decided to combine this drug with naltrexone because it offers similar virtues and can suppress the craving for sweet food.
When to use Mysimba?
Mysimba is usually prescribed to a person who needs medical intervention to help them control their weight. Be careful, this slimming drug is sold under prescription and must be used in conjunction with an adapted and low-calorie diet as well as with regular physical activity.
When you take Mysimba for the first time, you gradually increase the dose so that your body gets used to it. After 4 weeks, you should have reached the regular balanced dose that your doctor has prescribed. The latter will discuss with you how long you should take Mysimba. If your doctor advises you to take Mysimba for more than 16 weeks, then he should review his prescription in order to find the following dosage.
The Orexigen Therapeutics laboratory that designs Mysimba suggests that a person should lose 5% of their total body weight after 16 weeks of milking with this drug. He therefore recommends that the treatment be discontinued if no conclusive results are obtained at the end of this period.
Mysimba comes in the form of tablets in individual doses of 8 mg / 90 mg. Each tablet contains 8 mg of naltrexone hydrochloride, equivalent to 7.2 mg of naltrexone, and 90 mg of bupropion hydrochloride, equivalent to 78 mg of bupropion. Tablets should be swallowed whole with water without being chewed. Tablets should not be taken at the same time as high-fat meals as it is possible that the combination may cause an epileptic seizure.
Be careful, Mysimba tablets should only be taken by adults over 18 years of age.
Mysimba Dosage: The Treatment for Weight Loss
At the beginning of treatment with Mysimba, the current dosage is one tablet once a day in the morning. However, your doctor will tell you the appropriate dosage for your situation, which is usually:
- 1st week: 1 tablet once a day in the morning,
- 2nd week: 1 tablet twice a day, 1 in the morning and 1 in the evening,
- 3rd week: 3 tablets per day, 2 in the morning and one in the evening,
- Week 4 and beyond: 2 tablets twice a day, 2 in the morning and 2 in the evening.
The maximum daily dose recommended by the manufacturer of Mysimba is two tablets to be taken twice a day.
Mysimba: what side effects?
Like any slimming medication, Mysimba is likely to cause side effects, such as:
- insomnia,
- agitation,
- anxiety,
- headaches,
- impaired concentration,
- dizziness,
- hot flashes,
- palpitations,
- constipation,
- nausea,
- muscle pain,
- dry mouth sensation
Of course, if you experience any of these side effects, you should tell your doctor right away.
Are there any drug interactions with Mysimba?
Remember that people under the age of 18 should not take Mysimba appetite suppressant tablets. Similarly, it is not recommended to take this slimming drug if you are taking treatment with the following drugs:
- Monoamine oxidase inhibitors: medicines used to treat depression or Parkinson's disease, such as phenelzine, selegiline or rasagiline.
- Opiates or medicines containing opiates: certain medicines used to treat coughs and colds (for example, those containing codeine or dextromethorphan), medicines to combat opiate addiction (such as methadone), analgesics containing opiates (for example, codeine or morphine).
Indeed, naltrexone blocks the effects of opiates; If you take higher doses of opiates to overcome the effects of naltrexone, you could suffer from acute opioid poisoning that could be life-threatening.
So, before taking your Mysimba tablets, always check the ingredients of any medication you are taking in addition to informing your doctor. The active ingredients in some medications used to treat depression may combine with the ingredients in Mysimba and may eventually induce suicidal behavior. In any case, it is essential that you inform your doctor if you are taking medication for depression.
Even if they are not taking medication, anyone with a tendency to depression should be closely monitored by their doctor when taking Mysimba. It is not recommended to drink alcoholic beverages during treatment with Mysimba because the combination of alcohol and the slimming drug can increase the risk of seizure and cause mental disorders.
If you suffer from liver or kidney problems or are over 65 years of age, it is essential that your doctor examine you before any treatment with Mysimba. Finally, this appetite suppressant drug is not recommended for people over 75 years of age. Similarly, it should not be used during the period of pregnancy or during lactation.
Mysimba: our opinion on the appetite suppressant drug
As we will have understood, a treatment with Mysimba is not at all to be taken lightly. If it seems obvious that this drug seems effective for weight loss, its use should be closely monitored and should only be done in the context of severe obesity. While customer reviews suggest that Mysimba may indeed act for weight loss, its use can still lead to side effects.
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